yxjM [2019-08-12 13:34:44]

two-component sensor kinase

locus: BSU_38900

pI: 6.80

mw: 45.07 kDa

protein length: 406 aa

gene length: 1221 bp

function: unknown

product: two-component sensor kinase ([SW|NarL family])

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.1|Two-component sensor kinase]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue]

Gene

Coordinates: 3,993,162 3,994,382

The protein

Catalyzed reaction/ biological activity

• autophosphorylation, phosphorylation of [protein|23F365C23BDEE02D42C9355FC7D2A65DAF9F79ED|YxjL]

Modification

• autophosphorylation on a His residue

[SW|Localization]

• cell membrane (according to UniProt)

Biological materials

Mutant

• MGNA-B801 (yxjM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1800 NBRP B. subtilis, Japan]
• BKE38900 ([gene|6D10C9232F0D28973F7C3C6ECDFD6948928CB23F|yxjM]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE38900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTTCATGCTGGTCCTTCTTT, downstream forward: _UP4_ATGACAACGAATAAGGAGCA
• BKK38900 ([gene|6D10C9232F0D28973F7C3C6ECDFD6948928CB23F|yxjM]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK38900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTTCATGCTGGTCCTTCTTT, downstream forward: _UP4_ATGACAACGAATAAGGAGCA

References

• 10094672